Madhura teamed up with Shuai from the Gjorgjeva group to show that luminance gain control past photoreceptors is multi-faceted. Madhura and Shuai combined imaging and behavioral experiment with computational modeling to show that a single luminance-sensitive visual pathways (via L3 neurons) implements gain control at both fast and slow time scales. This computation is bidirectional in that it prevents underestimation of contrast in low luminance and overestimation of contrast in high luminance. It's remarkable how a single neuronal pathway can perform diverse computation to ensure stable processing of visual stimuli.
